Endocrine Abstracts

Introduction: Hyperandrogenism is a diagnostic feature for polycystic ovarian syndrome (PCOS). Androstenedione is a testosterone precursor that has been shown to be useful in diagnosis of PCOS especially in the setting of normal testosterone. During 2022, our laboratory in St Vincent’s University Hospital in Dublin, Ireland, changed from using a radioimmunoassay to an electrochemiluminescence immunoassay, which requires a non-gel tube in line with manufacturers requiremen...

Introduction: Hyperandrogenism causing virilisation in postmenopausal females is rare. It is caused by abnormal ovarian or adrenal androgen production, but establishing the source of androgen excess can be challenging. Testosterone levels >5 nmol/l can be associated with virilization (Hirschberg, 2022).Case: A 75-year-old post-menopausal woman, with a 3-year history of androgenic alopecia (Ludwig scale 3/3) and hirsutism (Ferrimen Gallwey Score 32/36...